DNA algorithm study proves 90% accurate prediction bowel cancer

DNA algorithm study proves 90% accurate prediction bowel cancer

Dominic hughes

Health Correspondent, BBC News

PA looks in a microscope in a lab, beating the knob on a female scientist deviceCountry

According to research, a new method to detect intestinal cancer is more than 90% accurate in predicting that high risk people will develop the disease.

About 500,000 people in the UK live with inflammatory bowel disease (IBD), including Crohn and ulcerative colitis.

Currently, they are offered regular check-ups for the development of pre-cancer in their intestine, which if detected, indicates a 30% possibility of bowel cancer of more than 10 years.

But the work done by the Institute of Cancer Research in London found DNA change in those pre-cancer cells when analyzed by an algorithm, it was more than 90% accurate to predict that the development of bowel cancer in the next five years Who will do it

Researchers used tissue samples from IBD patients – but it is expected that their method can be used to develop a simple blood test to identify those IBD patients at the most risk.

Craig Foster Craig Foster and his wife Farba are sitting shoulder to shoulder, both of them smiling directly on the camera. They are cleverly dressed which looks like a wedding. Fariba's shoulder length is brown hair.Craig Foster

Craig Foster’s wife, Fariba died of bowel cancer last year

Waterloville, Craig Foster from Hunts, “will save life from such research,” Hunts, Hunts, Craig Foster said in February 2024.

Farba was 18 years old, when she was 18 years old, she lived with ulcerative colitis when her three-fourth part of her bowel was removed.

Craig said, “It gives me a comfort to know that there are scientists working right now so that no one can experience the same situation that was in Fariba.”

“Six months after the diagnosis, Farba died.

“Even though it was a short time, it was the worst time.

“Cancer does not take a prisoner – and no matter who you are or with whom, everyone is affected in some way,”

The Institute of Cancer Research Professor Graham stands in a laboratory setting in front of jars and shelves filled with boxes. He is looking at the camera directly, wearing a white lab coat and glasses, with blonde hairCancer research institute

Prof Trevor Graham says that the new test should help identify those at high risk, who puts the minds of many others comfortably.

Professor of Institute of Cancer Research, Trever Graham said: “Most people with ulcerative colitis or Crohn’s disease will not develop bowel cancer.

“But for those who have these conditions and are indicating pre-cancer in their colon, some are for making difficult decisions.

“Either they have monitored it regularly, in the hope that it does not become cancer, or they have been removed to guarantee their bowel that they do not get cancer in the future.

“None of these options is particularly pleasant.

“Our tests and algorithms give people with IBD, and the doctors who take care of them, the best possible information so that they can take the right decisions about how to manage the risk of their cancer.”

‘Very exciting’

Charity Crohn and Collitis UK Marien Radcliffe said it was really positive news for those living with conditions.

“People tell us that one of the most difficult things about living with Crohn or Colitis is uncertainty – in everyday life and in the long term.

“Just with swollen bowel disease, we know that first you know about cancer, it is better.

“Anything that enables early, with less aggressive clinical trials to detect early, removing some of that uncertainty is extremely exciting.”

‘Focus Resources’

Cancer Research UK Dr. Ian Fallks, who funded research, says progress in technology is reopening the understanding of diseases such as cancer.

“Genome sequencing is now more cheap and more wider than ever – and it is changing how we see cancer,” he said.

“Getting full readouts of tumor DNA means that we can see a large picture of someone’s onset and how it is likely to change over time.

“With this research, we can focus on resources on the treatment of people with IBDs that are actually at high risk, saving valuable time and money to health services.

“We can also give those people at a low -risk peace of mind and remove the fear of bowel cancer in the future.”

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